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735-737 Japanese smallpox epidemic vs. Plague of...
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735-737 Japanese smallpox epidemic vs Plague of Justinian (Bubonic plague) 541-549

735-737 Japanese smallpox epidemic
Plague of Justinian (Bubonic plague) 541-549
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735-737 Japanese smallpox epidemic

Total costsN/A
Deaths 2000000

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The 735–737 Japanese smallpox epidemic (天平の疫病大流行, Tenpyō no ekibyō dairyūkō, 'Epidemic of the Tenpyō era') was a major smallpox epidemic that afflicted much of Japan. Killing approximately 1/3 of the entire Japanese population, the epidemic had significant social, economic, and religious repercussions throughout the country.

Source: Wikipedia
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Plague of Justinian (Bubonic plague) 541-549

Total costsN/A
Deaths 100000000

Informations

The plague of Justinian or Justinianic plague (541–549 AD) was the first major outbreak of the first plague pandemic, the first Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. The disease afflicted the entire Mediterranean Basin, Europe, and the Near East, severely affecting the Sasanian Empire and the Byzantine Empire and especially its capital, Constantinople. The plague is named for the Byzantine emperor in Constantinople, Justinian I (r. 527–565) who, according to his court historian Procopius, contracted the disease and recovered in 542, at the height of the epidemic which killed about a fifth of the population in the imperial capital. The contagion arrived in Roman Egypt in 541, spread around the Mediterranean Sea until 544, and persisted in Northern Europe and the Arabian Peninsula, until 549.In 2013, researchers confirmed earlier speculation that the cause of the plague of Justinian was Yersinia pestis, the same bacterium responsible for the Black Death (1347–1351). Ancient and modern Yersinia pestis strains closely related to the ancestor of the Justinian plague strain have been found in the Tian Shan, a system of mountain ranges on the borders of Kyrgyzstan, Kazakhstan, and China, suggesting that the Justinian plague originated in or near that region.

Source: Wikipedia

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