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Heidelberg ( HY-dəl-burg, German: [ˈhaɪdl̩bɛʁk] (listen)) is a university town in the German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. In the 2016 census, its population was 159,914, of which roughly a quarter consisted of students.Located about 78 km (48 mi) south of Frankfurt, Heidelberg is the fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar Metropolitan Region.
Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a scientific hub in Germany and home to several internationally renowned research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Institutes.
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Madrid (, Spanish: [maˈðɾið]) is the capital and most-populous city of Spain. The city has almost 3.3 million inhabitants and a metropolitan area population of approximately 6.5 million. It is the second-largest city in the European Union (EU), surpassed only by Berlin, and its monocentric metropolitan area is the second-largest in the EU, surpassed only by Paris. The municipality covers 604.3 km2 (233.3 sq mi).Madrid lies on the River Manzanares in the center of both the country and the Community of Madrid region, of which it is also the capital. As the capital city of Spain, seat of government, residence of the Spanish monarch, Madrid is also the political, economic and cultural centre of the country. The mayor is José Luis Martínez-Almeida from the People's Party.
The Madrid urban agglomeration has the third-largest GDP in the European Union and its influence in politics, education, entertainment, environment, media, fashion, science, culture, and the arts all contribute to its status as one of the world's major global cities. Madrid is home to two world-famous football clubs, Real Madrid and Atlético Madrid. Due to its economic output, high standard of living, and market size, Madrid is considered the major financial centre and the leading economic hub of the Iberian Peninsula and of Southern Europe. It hosts the head offices of the vast majority of major Spanish companies, such as Telefónica, IAG or Repsol. Madrid is also the 10th most liveable city in the world according to Monocle magazine, in its 2017 index.